Analytical Tools Integrated in Continuous-Flow Reactors: Which One for What?

The concept and practices of chemical synthesis are being profoundly transformed toward the development fully autonomous continuous processes. Critical to processes is efficient monitoring reaction composition product quality by in-line online analyses. in-line/online acquisition analytical data allows one monitor at regular intervals composition, including hazardous or air-sensitive intermediates with possibility adapting parameters interrupting flow process when a technical failure detected. This review presents main tools that can be integrated into reactors for reactions. contribution more guide service synthetic chemists illustrated selected published examples from leading research laboratories than an exhaustive list articles. Ultimately, we would like this answer following recurrent, yet complex, question: “Which is/are most suitable solution(s) my reaction?”.